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  • Promoting Informed Decision Making for Comparative Effectiveness Randomized Trials

    Abstract Full Text
    JAMA Pediatr. 2015; 169(9):803-804. doi: 10.1001/jamapediatrics.2015.0906

    This Viewpoint proposes that disclosures in comparative effectiveness randomized clinical trials should provide patients with appropriate information, including about risks, that are necessary to decide whether to join the trial, request a study treatment outside the trial, or select another available treatment.

  • Children's and Their Parents' Views on Facing Research Risks for the Benefit of Others

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    Arch Pediatr Adolesc Med. 2008; 162(1):9-14. doi: 10.1001/archpediatrics.2007.3
  • Empirical Data and the Acceptability of Research Risk: A Commentary on the Charitable Participation Standard

    Abstract Full Text
    Arch Pediatr Adolesc Med. 2008; 162(1):88-90. doi: 10.1001/archpediatrics.2007.4
  • JAMA Pediatrics January 1, 2008

    Table 1: Children's and Their Parents' Views on Facing Research Risks for the Benefit of Others

    Sociodemographics of Survey Participantsa
  • JAMA Pediatrics January 1, 2008

    Table 2: Children's and Their Parents' Views on Facing Research Risks for the Benefit of Others

    Reasons for Preferring That Children Participate in Nonbeneficial Research or Charitya
  • JAMA Pediatrics January 1, 2008

    Table 3: Children's and Their Parents' Views on Facing Research Risks for the Benefit of Others

    Willingness to Have Child Face Risks to Help Othersa
  • Risk Factors for Adverse Events in Emergency Department Procedural Sedation for Children

    Abstract Full Text
    JAMA Pediatr. 2017; 171(10):957-964. doi: 10.1001/jamapediatrics.2017.2135

    This multicenter cohort study examines the procedural sedation practices, adverse events, and risk factors for children undergoing painful procedures in Canadian emergency departments.

  • Association of Short Antenatal Corticosteroid Administration-to-Birth Intervals With Survival and Morbidity Among Very Preterm Infants: Results From the EPICE Cohort

    Abstract Full Text
    JAMA Pediatr. 2017; 171(7):678-686. doi: 10.1001/jamapediatrics.2017.0602

    This population-based cohort study explores the associations between antenatal corticosteroid administration-to-birth interval and survival and morbidity among very preterm infants.

  • Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections

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    JAMA Pediatr. 2017; 171(11):e172927. doi: 10.1001/jamapediatrics.2017.2927

    This cohort study estimates the accuracy of individual complete blood cell count parameters to identify febrile infants with invasive bacterial infections.

  • Association of Antenatal Corticosteroids With Mortality, Morbidity, and Neurodevelopmental Outcomes in Extremely Preterm Multiple Gestation Infants

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    JAMA Pediatr. 2016; 170(6):593-601. doi: 10.1001/jamapediatrics.2016.0104

    This cohort study examines if use of antenatal corticosteroids is associated with improvement in major outcomes in extremely preterm multiples.

  • Comparative Effectiveness of Intravenous vs Oral Antibiotics for Postdischarge Treatment of Acute Osteomyelitis in Children

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    JAMA Pediatr. 2015; 169(2):120-128. doi: 10.1001/jamapediatrics.2014.2822

    This retrospective cohort study suggests that clinicians reconsider the practice of treating otherwise healthy children with acute osteomyelitis with prolonged intravenous antibiotics when an equally effective oral alternative exists.

  • Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease

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    JAMA Pediatr. 2016; 170(10):e161971. doi: 10.1001/jamapediatrics.2016.1971

    This study assesses the prevalence of type 2 diabetes and prediabetes in children with nonalcoholic fatty liver disease and assesses type 2 diabetes and prediabetes as risk factors for nonalcoholic steatohepatitis.

  • Validation and Refinement of a Prediction Rule to Identify Children at Low Risk for Acute Appendicitis

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    Arch Pediatr Adolesc Med. 2012; 166(8):738-744. doi: 10.1001/archpediatrics.2012.490
    The diagnosis of appendicitis can be difficult in children. Kharbanda et al sought to validate and refine a clinical prediction rule for pediatric appendicitis by identifying a population with suspected appendicitis at low but not zero risk for the condition.
  • Isolated Loss of Consciousness in Children With Minor Blunt Head Trauma

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    JAMA Pediatr. 2014; 168(9):837-843. doi: 10.1001/jamapediatrics.2014.361

    Lee and colleagues aimed to determine the risk for clinically important traumatic brain injuries in children with isolated loss of consciousness.

  • Surgery and Neurodevelopmental Outcome of Very Low-Birth-Weight Infants

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    JAMA Pediatr. 2014; 168(8):746-754. doi: 10.1001/jamapediatrics.2014.307

    Morriss et al assess the association between surgery during the initial hospitalization and death or neurodevelopmental impairment of very low-birth-weight infants. See the editorial by Williams et al.

  • Association of Persistent Postconcussion Symptoms With Pediatric Quality of Life

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    JAMA Pediatr. 2016; 170(12):e162900. doi: 10.1001/jamapediatrics.2016.2900

    This multicenter cohort study examines the association between health-related quality of life and persistent postconcussion symptoms at 4 weeks after concussion and the degree of impairment of health-related quality of life in the subsequent 12 weeks.

  • Association of Neurodevelopmental Outcomes and Neonatal Morbidities of Extremely Premature Infants With Differential Exposure to Antenatal Steroids

    Abstract Full Text
    JAMA Pediatr. 2016; 170(12):1164-1172. doi: 10.1001/jamapediatrics.2016.1936

    This observational cohort study compares rates of neonatal morbidities and 18- to 22-month neurodevelopmental outcomes of extremely premature infants exposed to partial or complete courses of antenatal steroids vs those exposed to no antenatal steroids.

  • Complicated Grief and Associated Risk Factors Among Parents Following a Child's Death in the Pediatric Intensive Care Unit

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    Arch Pediatr Adolesc Med. 2010; 164(11):1045-1051. doi: 10.1001/archpediatrics.2010.187
  • Cranial Computed Tomography Use Among Children With Minor Blunt Head Trauma: Association With Race/Ethnicity

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    Arch Pediatr Adolesc Med. 2012; 166(8):732-737. doi: 10.1001/archpediatrics.2012.307
    To determine if race/ethnicity is independently associated with cranial computed tomography use, Natale and colleagues analyzed 39 717 children younger than 18 years who were seen in the emergency department within 24 hours of minor blunt head trauma, stratified by white non-Hispanic, black non-Hispanic, or Hispanic race/ethnicity and classified for clinically important traumatic brain injury.
  • Chorioamnionitis and Early Childhood Outcomes Among Extremely Low-Gestational-Age Neonates

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    JAMA Pediatr. 2014; 168(2):137-147. doi: 10.1001/jamapediatrics.2013.4248

    Pappas et al for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network compare the neonatal and neurodevelopmental outcomes of 3 groups of extremely low-gestational-age infants with increasing exposure to perinatal inflammation.