Tamma et al determined whether definitive combination antibiotic therapy affects mortality and nephrotoxicity in pediatric patients with gram-negative bacteremia.
This cohort study used a comprehensive database shared by 6 hospitals to determine the association between the administration of combination therapy for serious infections and the development of acute kidney injury in hospitalized children.
This study evaluates whether delay in the initiation of antimicrobial therapy for pediatric febrile urinary tract infections is associated with the occurrence and severity of renal scarring.
This cohort study compares readmission rates in children with sickle cell disease and acute chest syndrome who receive guideline-adherent vs other antibiotic therapies.
This cohort study tests the association between early-life antibiotic use and islet or celiac disease autoimmunity in genetically at-risk children prospectively followed up for type 1 diabetes or celiac disease.
This cohort study compares the effectiveness of β-lactam monotherapy vs β-lactam plus macrolide combination therapy among children hospitalized with pneumonia.
This meta-analysis compares the safety and efficacy of antibiotic treatment vs appendectomy as the primary therapy for acute uncomplicated appendicitis in pediatric patients.
This secondary analysis of randomized clinical trial data examines whether prolonged antibiotic exposure is associated with weight gain in children with vesicoureteral reflux taking antibiotic prophylaxis to prevent recurrent urinary tract infection.
This study examines the effect of neonatal early-onset sepsis risk prediction models on sepsis evaluations and antibiotic use and assesses their safety in a large integrated health care system.
This cohort study examines whether early-life antibiotic use in children is associated with the long-term effects of breastfeeding on weight development and lifetime antibiotic use.
This population epidemiology study describes the incidence and clinical characteristics of Staphylococcus aureus bacteremia in children in Australia and New Zealand between 2007 and 2012.
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