This review provides an overview of data suggesting how different environmental factors may modulate the risk of developing inflammatory bowel diseases including diet, smoking, lifestyle choices, enteric infections, appendectomy, air pollution, and the use of medications, especially antibiotics.
This study examines the association between time to appendectomy and risk of complicated appendicitis and postoperative complications.
This meta-analysis compares the safety and efficacy of antibiotic treatment vs appendectomy as the primary therapy for acute uncomplicated appendicitis in pediatric patients.
This database review reports that use of diagnostic ultrasonography has increased and that of computed tomography has decreased in children with suspected appendicitis, resulting in a decline in negative appendectomy at 35 pediatric institutions.
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