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 Showing 21-26 of 26 Articles
Original Investigation 
Umar Toseeb, PhD; Soren Brage, PhD; Kirsten Corder, PhD; Valerie J. Dunn, BEd; Peter B. Jones, MD, PhD, MRCPsych; Matthew Owens, PhD; Michelle C. St Clair, PhD; Esther M. F. van Sluijs, PhD; Ian M. Goodyer, MD, FRCPsych

Importance  Physical activity (PA) may have a positive effect on depressed mood. However, whether it can act as a protective factor against developing depressive symptoms in adolescence is largely unknown.

Objective  To investigate the association between objectively measured PA and depressive symptoms during 3 years of ...

Alan R. Fleischman, MD; Mildred Z. Solomon, EdD
This Viewpoint addresses questions raised in the debate over whether the current US regulatory framework for governing protection of human research participants is an impediment to comparative effectiveness research.
Original Investigation 
Adam J. Spanier, MD, PhD, MPH; Robert S. Kahn, MD, MPH; Allen R. Kunselman, MA; Eric W. Schaefer, MS; Richard Hornung, DrPH; Yingying Xu, MS; Antonia M. Calafat, PhD; Bruce P. Lanphear, MD, MPH

Importance  Bisphenol A (BPA), a prevalent endocrine-disrupting chemical, has been associated with wheezing in children, but few studies have examined its effect on lung function or wheeze in older children.

Objectives  To test whether BPA exposure is associated with lung function, with wheeze, and with pattern ...

Original Investigation 
Deborah Persaud, MD; Kunjal Patel, DSc, MPH; Brad Karalius, MPH; Kaitlin Rainwater-Lovett, PhD, MPH; Carrie Ziemniak, MS; Angela Ellis, BS; Ya Hui Chen, BA; Douglas Richman, MD; George K. Siberry, MD, MPH; Russell B. Van Dyke, MD; Sandra Burchett, MD; George R. Seage III, DSc, MPH; Katherine Luzuriaga, MD; for the Pediatric HIV/AIDS Cohort Study

Importance  Combination antiretroviral therapy initiated within several weeks of human immunodeficiency virus (HIV) infection in adults limits proviral reservoirs that preclude HIV cure. Biomarkers of restricted proviral reservoirs may aid in the monitoring of HIV remission or cure.

Objectives  To quantify peripheral blood proviral reservoir size ...

Annual Reviewers List  FREE
Frederick P. Rivara, MD, MPH
“You mean you do that for free? Why would you spend the time? What's in it for you?”
Alain Joffe, MD, MPH; Frederick P. Rivara, MD, MPH
How best to transition adolescents and young adults—particularly medically complex individuals or those with a chronic illness or disability—from a pediatric to an adult system of health care remains a largely unanswered question. Challenges to a smooth transition include being able to identify those most in need of transition planning, ...

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