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 Showing 1-20 of 31 Articles
Editorial 
Pranita D. Tamma, MD, MHS; Aaron M. Milstone, MD, MHS
The ability to provide long-term antibiotic therapy for acute osteomyelitis was revolutionized by the use of peripherally inserted central catheters (PICCs). Peripherally inserted central catheters provided an alternative for children to receive antibiotic therapy outside the health care setting, which reduced their hospital length of stay and improved their quality ...
Original Investigation  FREE
Ron Keren, MD, MPH; Samir S. Shah, MD, MSCE; Rajendu Srivastava, MD, FRCPC, MPH; Shawn Rangel, MD; Michael Bendel-Stenzel, MD; Nada Harik, MD; John Hartley, DO; Michelle Lopez, MD; Luis Seguias, MD; Joel Tieder, MD; Matthew Bryan, PhD; Wu Gong, MS; Matt Hall, PhD; Russell Localio, PhD; Xianqun Luan, MS; Rachel deBerardinis, BA; Allison Parker, MS; for the Pediatric Research in Inpatient Settings Network
Includes: Supplemental Content, Multimedia: (powerpoint)

Importance  Postdischarge treatment of acute osteomyelitis in children requires weeks of antibiotic therapy, which can be administered orally or intravenously via a peripherally inserted central catheter (PICC). The catheters carry a risk for serious complications, but limited evidence exists on the effectiveness of oral therapy.

Objective  ...

Review 
Valerio Nobili, MD; Naim Alkhouri, MD; Anna Alisi, PhD; Claudia Della Corte, MD; Emer Fitzpatrick, MD; Massimiliano Raponi, MD; Anil Dhawan, MD

Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and is considered the most common form of chronic liver disease in children. Several factors contribute to NAFLD development, including race/ethnicity, genetic factors, environmental exposures, and alterations in the gut microbiome. The histologic spectrum of ...

To the Editor In the article recently published in JAMA Pediatrics on a cluster randomized trial of the Healthy Buddies program, Santos and colleagues1 reported effect sizes for the impact of intervention on the assessed outcomes, with waist circumference and body mass index z scores serving as primary outcomes. The ...
Comment & Response 
Robert G. Santos, PhD; Anita Durksen, MSc; Jonathan M. McGavock, PhD
In Reply On behalf of my coauthors, I thank Dr Dubois for highlighting the error of reporting treatment effect in the article that described the results of the cluster randomized clinical trial of the Healthy Buddies Curriculum, recently published in JAMA Pediatrics.1 Dr Dubois correctly highlighted the fact that the ...
Correction  FREE
In the article titled “Effectiveness of Peer-Based Healthy Living Lesson Plans on Anthropometric Measures and Physical Activity in Elementary School Students: A Cluster Randomized Trial,” published online February 10, 2014, and also in the April 2014 print issue of JAMA Pediatrics (2014;168[4]:330-337. doi:10.1001/jamapediatrics.2013.3688), several minor errors existed in the statistical ...
Viewpoint 
Nancy A. Dodson, MD, MPH; David Hemenway, PhD
At a meeting of the Greater Boston Interfaith Organization in April 2013, Mirna Luz Ramos takes the microphone. With a cracking voice and tears, she talks about her 19-year-old son, Jorge. He was shot and killed while walking the dog outside of her home. She found him dying on the ...
Original Investigation 
Cheryl K. Walker, MD; Paula Krakowiak, PhD; Alice Baker, MPH; Robin L. Hansen, MD; Sally Ozonoff, PhD; Irva Hertz-Picciotto, PhD
Includes: Supplemental Content

Importance  Increasing evidence suggests that autism spectrum disorder (ASD) and many forms of developmental delay (DD) originate during fetal development. Preeclampsia may trigger aberrant neurodevelopment through placental, maternal, and fetal physiologic mechanisms.

Objective  To determine whether preeclampsia is associated with ASD and/or DD.

Design, Setting, and ...

Original Investigation 
Samir Soneji, PhD; James D. Sargent, MD; Susanne E. Tanski, MD, MPH; Brian A. Primack, MD, PhD
Includes: Supplemental Content

Importance  Many adolescents and young adults use alternative tobacco products, such as water pipes and snus, instead of cigarettes.

Objective  To assess whether prior water pipe tobacco smoking and snus use among never smokers are risk factors for subsequent cigarette smoking.

Design, Setting, and Participants  ...

Viewpoint 
Julia Potter, MD; Atsuko Koyama, MD, MPH; Mandy S. Coles, MD, MPH
Long-acting reversible contraceptive (LARC) methods are gaining greater popularity in the United States as both patients and health care professionals become educated about their high contraceptive efficacy, relatively few contraindications, and ease of use. In fact, LARC is recommended by the American Congress of Obstetricians and Gynecologists and the American ...
Original Investigation 
Kristin Bernard, PhD; Camelia E. Hostinar, PhD; Mary Dozier, PhD

Importance  A number of interventions for at-risk children have shown benefits for children’s hypothalamic-pituitary-adrenal axis activity immediately after treatment. It is critical to examine whether such changes are maintained over time, given that physiological regulation is implicated in later mental and physical health outcomes.

Objective  To ...

Original Investigation 
Denise Kendrick, DM; Asiya Maula, MPH; Richard Reading, MD; Paul Hindmarch, MA; Carol Coupland, PhD; Michael Watson, PhD; Mike Hayes, PhD; Toity Deave, PhD
Includes: Supplemental Content

Importance  Falls from furniture are common in young children but there is little evidence on protective factors for these falls.

Objective  To estimate associations for risk and protective factors for falls from furniture in children aged 0 to 4 years.

Design, Setting, and Participants  Multicenter ...

A groundbreaking study,1 published in this journal nearly 25 years ago, documented improved academic outcomes among low-income schoolchildren who received school breakfast via the School Breakfast Program (SBP) vs those who did not, including significantly decreased tardiness and absences and improved performance on standardized tests of academic achievement. Since that ...
In this issue of JAMA Pediatrics, Caruso and Cullen1 describe the nutritional quality and cost of lunch brought from home by elementary and intermediate school–aged children in Houston, Texas. As they remind us, this component of the school food environment is basically avoided by public health policy and rarely addressed ...
Original Investigation 
Stephanie Anzman-Frasca, PhD; Holly Carmichael Djang, MA; Megan M. Halmo, MPH, MSW; Peter R. Dolan, MBA; Christina D. Economos, PhD

Importance  Short-term impacts of breakfast consumption on diet quality and cognitive functioning have been reported, but more evidence is needed to draw causal inferences about long-term impacts of school breakfast on indicators of school engagement and academic achievement.

Objective  To estimate the impact of a Breakfast ...

Original Investigation 
Michelle L. Caruso, MPH, RD; Karen W. Cullen, DrPH, RD

Importance  The nutritional quality and cost of lunches brought from home are overlooked and understudied aspects of the school food environment.

Objectives  To examine the quality and cost of lunches brought from home by elementary and intermediate school students.

Design, Setting, and Participants  An observational ...

Original Investigation 
Chris Feudtner, MD, PhD, MPH; Jennifer K. Walter, MD, PhD, MS; Jennifer A. Faerber, PhD; Douglas L. Hill, PhD; Karen W. Carroll, BS; Cynthia J. Mollen, MD, MSCE; Victoria A. Miller, PhD; Wynne E. Morrison, MD, MBE; David Munson, MD; Tammy I. Kang, MD, MSCE; Pamela S. Hinds, PhD, RN

Importance  Parents’ beliefs about what they need to do to be a good parent when their children are seriously ill influence their medical decisions, and better understanding of these beliefs may improve decision support.

Objective  To assess parents’ perceptions regarding the relative importance of 12 good-parent ...

Viewpoint 
Jeffrey P. Brosco, MD, PhD; Scott D. Grosse, PhD; Lainie Friedman Ross, MD, PhD
Fifty years after the advent of state newborn screening (NBS) programs for a metabolic condition, there is evidence that the decision to mandate universal screening can reduce health disparities. When in-hospital screening for phenylketonuria began in the early 1960s, most hospitals simply added the procedure to the list of routine ...
Viewpoint 
Jonathan Todres, JD
On November 20, 2014, the global community will celebrate the 25th anniversary of the United Nations Convention on the Rights of the Child, the most comprehensive international legal instrument on children’s rights. The Convention is the most widely ratified human rights treaty in history, ratified by 194 countries. Only the ...
Editorial 
Leslie A. Lytle, PhD
The study by Terry-McElrath et al1 in the current issue of JAMA Pediatrics seeks to answer important, timely questions related to how the new federal policy issued by the US Department of Agriculture (USDA) may affect the nutritional environment of US schools and childhood obesity rates. Beginning in the 2014-2015 ...

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