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 Showing 1-20 of 30 Articles
Sarah M. Wood, MD, AAHIVS; Nadia Dowshen, MD, AAHIVS; Elizabeth Lowenthal, MD, MSCE, AAHIVS

This Viewpoint discusses the importance of improving care globally for adolescents with human immunodeficiency virus (HIV)/AIDS.

Original Investigation 
Soyang Kwon, PhD; Kathleen F. Janz, EdD; Elena M. Letuchy, MS; Trudy L. Burns, PhD; Steven M. Levy, DDS
Includes: Supplemental Content

Importance  The diverse developmental patterns of obesogenic behaviors during childhood and adolescence can be better understood by using new analytic approaches to assess the heterogeneity in variation during growth and development and to map the clustering of behavior patterns.

Objectives  To identify distinct trajectories of daily ...

Original Investigation  FREE
Jeffrey A. Bridge, PhD; Lindsey Asti, MPH; Lisa M. Horowitz, PhD, MPH; Joel B. Greenhouse, PhD; Cynthia A. Fontanella, PhD; Arielle H. Sheftall, PhD; Kelly J. Kelleher, MD; John V. Campo, MD

Importance  Suicide is a leading cause of death among school-aged children younger than 12 years but little is known about the epidemiology of suicide in this age group.

Objective  To describe trends in suicide among US children younger than 12 years by sociodemographic group and method ...

The National Health and Nutrition Examination Survey data suggest a plateauing of childhood obesity in the United States, with no trend among children younger than 11 years since 1999.1,2 However, studies have challenged this finding and cautioned that the overall static trend masks significant differences ...

Meaghann Shaw Weaver, MD, MPHc; Liza-Marie Johnson, MD, MSB, MPH

This Viewpoint reports that global health outreach partnerships with a bioethical foundation have the potential for immense societal benefit, personal growth, and professional enhancement for pediatric trainees.

Matthew W. Gillman, MD, SM; Jason P. Block, MD, MPH

This Editorial discusses the need to provide evidence-based therapies that are as personalized as possible to children with obesity, while not making these children feel different from their peers in ways that are harmful.

Original Investigation  FREE
Justin Stiers, MD; Cecile Aguayo, RN, CCTC; Angela Siatta, RN, CPTC; Angela P. Presson, PhD; Richard Perez, MD; Robert DiGeronimo, MD
Includes: Supplemental Content, Multimedia: (powerpoint)

Importance  The need for transplants continues to exceed organ and tissue donor availability. Although recent surgical advances have resulted in successful transplants using very small pediatric donors, including neonates, the actual practice of neonatal organ donation after circulatory determination of death (DCDD) remains uncommon.

Objective  To ...

Margreet W. Harskamp-van Ginkel, MD; Kevin D. Hill, MD; Kristian Becker, BA; Daniela Testoni, MD, MHS; Michael Cohen-Wolkowiez, MD, PhD; Daniel Gonzalez, PharmD, PhD; Jeffrey S. Barrett, PhD; Daniel K. Benjamin Jr, MD, PhD, MPH; David A. Siegel, MD; Patricia Banks, BS; Kevin M. Watt, MD; for the Best Pharmaceuticals for Children Act–Pediatric Trials Network Administrative Core Committee
Includes: Supplemental Content

Importance  Obesity affects nearly one-sixth of US children and results in alterations to body composition and physiology that can affect drug disposition, possibly leading to therapeutic failure or toxic side effects. The depth of available literature regarding obesity’s effect on drug safety, pharmacokinetics, and dosing in obese ...

Editorial: Children With Obesity; Matthew W. Gillman, MD, SM; Jason P. Block, MD, MPH
Kristen A. Feemster, MD, MPH, MSHP

Between 2009 and 2012, 36 bills were introduced in 18 states to change vaccine exemption laws related to school-entry requirements. Of the 31 bills that sought to loosen requirements for obtaining an exemption, none passed.1 Fortunately, the clear evidence showing that easy exemption laws lead to higher ...

Original Investigation 
Thomas P. Dompier, PhD, ATC; Zachary Y. Kerr, PhD, MPH; Stephen W. Marshall, PhD; Brian Hainline, MD; Erin M. Snook, PhD; Ross Hayden, MA; Janet E. Simon, PhD, ATC

Importance  A report by the Institute of Medicine called for comprehensive nationwide concussion incidence data across the spectrum of athletes aged 5 to 23 years.

Objective  To describe the incidence of concussion in athletes participating in youth, high school, and collegiate American football.

Design, Setting, and ...

Original Investigation  FREE
Andrea C. Farnham, MPH; Christopher M. Zimmerman, MD, MPH; Vikki Papadouka, PhD, MPH; Kevin J. Konty, MS, MA; Jane R. Zucker, MD, MSc; Geetha V. Nattanmai, BS, MT, MS; Sherly Jose, AAS, CLT; Jennifer B. Rosen, MD

Importance  Invasive pneumococcal disease (IPD) is a leading cause of pneumonia, meningitis, and bacteremia in children. In March 2010, a 13-valent pneumococcal conjugate vaccine (PCV13) was introduced to the routine childhood immunization schedule. The PCV13 contains 6 serotypes not included in the previously recommended 7-valent pneumococcal conjugate ...

Editorial: Remembering the Benefits of Vaccination; Kristen A. Feemster, MD, MPH, MSHP
Original Investigation 
Dominique Petit, PhD; Marie-Hélène Pennestri, PhD; Jean Paquet, PhD; Alex Desautels, MD, PhD; Antonio Zadra, PhD; Frank Vitaro, PhD; Richard E. Tremblay, PhD; Michel Boivin, PhD; Jacques Montplaisir, MD, PhD

Importance  Childhood sleepwalking and sleep terrors are 2 parasomnias with a risk of serious injury for which familial aggregation has been shown.

Objectives  To assess the prevalence of sleepwalking and sleep terrors during childhood; to investigate the link between early sleep terrors and sleepwalking later in ...

Renee D. Boss, MD, MHS; Carrie M. Henderson, MD; Benjamin S. Wilfond, MD

This Viewpoint discusses the importance of effective patient-physician communication when addressing high-stakes medical decisions.

Original Investigation 
Sharon Bout-Tabaku, MD, MSCE; Marc P. Michalsky, MD; Todd M. Jenkins, PhD; Amy Baughcum, PhD; Meg H. Zeller, PhD; Mary L. Brandt, MD; Anita Courcoulas, MD; Ralph Buncher, ScD; Michael Helmrath, MD; Carroll M. Harmon, MD, PhD; Mike K. Chen, MD; Thomas H. Inge, MD, PhD

Importance  Obesity is associated with chronic musculoskeletal pain and is a risk factor for disability and osteoarthritis.

Objectives  To describe the prevalence, sites, and intensity of musculoskeletal pain in adolescents with severe obesity; to evaluate associations between musculoskeletal pain and self-reported physical function as well as ...

Original Investigation 
Justin R. Buendia, BS; M. Loring Bradlee, MS; Stephen R. Daniels, MD, PhD; Martha R. Singer, MPH, RD; Lynn L. Moore, DSc, MPH
Includes: Supplemental Content

Importance  Identification of risk factors early in life for the development of high blood pressure is critical to the prevention of cardiovascular disease.

Objective  To study prospectively the effect of dietary sodium, potassium, and the potassium to sodium ratio on adolescent blood pressure.

Design, Setting, and ...

Research Letter 
Hong Liu, MD; Yuan Zhang, MD, PhD; Hai-Tao Gu, MD, PhD; Qiao-Ling Feng, MD, MSc; Jia-Yin Liu, MD, PhD; Jie Zhou, MD; Fei Yan, PhD

Assisted reproductive technology (ART) has extensively permitted thousands of childbirths per year for many infertile couples throughout the world.1 Although ART is generally considered safe, a growing body of evidence reveals the association of ART with increased risk for poorer perinatal outcomes and congenital malformations.2 Furthermore, ...

Original Investigation 
Elsie M. Taveras, MD, MPH; Richard Marshall, MD; Ken P. Kleinman, ScD; Matthew W. Gillman, MD, SM; Karen Hacker, MD, MPH; Christine M. Horan, MPH; Renata L. Smith, MPH; Sarah Price, MPH; Mona Sharifi, MD, MPH; Sheryl L. Rifas-Shiman, MPH; Steven R. Simon, MD, MPH
Includes: Supplemental Content

Importance  Evidence of effective treatment of childhood obesity in primary care settings is limited.

Objective  To examine the extent to which computerized clinical decision support (CDS) delivered to pediatric clinicians at the point of care of obese children, with or without individualized family coaching, improved body ...

Original Investigation 
Li Ming Wen, MD, MMed, PhD; Louise A. Baur, MBBS, PhD; Judy M. Simpson, PhD; Huilan Xu, MBiostat, MPH; Alison J. Hayes, PhD; Louise L. Hardy, MPH(Hons), PhD; Mandy Williams, MHP; Chris Rissel, PhD

Importance  Little evidence exists on whether effects of an early obesity intervention are sustainable.

Objective  To assess the sustainability of effects of a home-based early intervention on children’s body mass index (BMI) and BMI z score at 3 years after intervention.

Design, Setting, and Participants  ...

David J. McLario, DO, MS; Adam B. Sivitz, MD

Importance  Point-of-care (POC) ultrasound has been used by a variety of nonradiologist physicians. Recently, POC ultrasound use by pediatricians has received increased attention with the practice of both established and novel applications.

Objectives  To review various uses of ultrasound by pediatricians, discuss challenges and potential pitfalls ...

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