TY - JOUR T1 - GRowth hormone treatment in children with sporadic primary microcephaly AU - Spadoni G, Cianfarani S, Bernardini S, Fabrizio V, Galasso C, Boscherini B Y1 - 1989/11/01 N1 - 10.1001/archpedi.1989.02150230040019 JO - American Journal of Diseases of Children SP - 1282 EP - 1283 VL - 143 IS - 11 N2 - • Four children with sporadic primary microcephaly associated with short stature, delayed bone age, and low growth velocity are described. All of the children showed a normal growth hormone response to standard pharmacological tests but one of the patients had a reduced spontaneous growth hormone nocturnal secretion. Regardless of the results of their somatotropic function evaluation, the patients were treated with exogenous growth hormone and all of them showed an increase in growth rate.(AJDC. 1989;143:1282-1283) SN - 0002-922X M3 - doi: 10.1001/archpedi.1989.02150230040019 UR - http://dx.doi.org/10.1001/archpedi.1989.02150230040019 ER -