TY - JOUR T1 - Clear heads and bayesian tales: Predictive value and the coin toss?-reply AU - BROWN GW Y1 - 1989/09/01 N1 - 10.1001/archpedi.1989.02150210017010 JO - American Journal of Diseases of Children SP - 1001 EP - 1001 VL - 143 IS - 9 N2 - —Dr Mauro has pointed out a very interesting aspect of the algebra of calculating positive predictive values or PV +.PV+ is the probability that this subject has the disease tested for (D +) given that the test for the disease is positive (T +). PV+ can be written as prob(D + T +) = the probability of the disease given a positive test.This is a classic Bayes' formula issue and a subtle one that I have not seen discussed anywhere in my reading. For the record, I will go through the algebra in case someone challenges Dr Mauro's assertions.If you flip a coin instead of performing a test, you will get pr(T + D +) of.50; that is, the probability of a positive test T+ is the probability of, say, "heads."Also, the probability of a positive test among subjects without the disease, pr(T + D-), will also be SN - 0002-922X M3 - doi: 10.1001/archpedi.1989.02150210017010 UR - http://dx.doi.org/10.1001/archpedi.1989.02150210017010 ER -