TY - JOUR T1 - TWice-daily therapy for strep?-reply AU - GERBER MA Y1 - 1989/09/01 N1 - 10.1001/archpedi.1989.02150210013003 JO - American Journal of Diseases of Children SP - 997 EP - 997 VL - 143 IS - 9 N2 - In Reply.—In the conclusion of our article,1 we attempted to make a distinction between our recommendations and those of the AHA. As Dr Gill has correctly observed, the AHA does not list twice-daily penicillin therapy as an acceptable regimen for the treatment of streptococcal pharyngitis.2 However, based on our findings3 and those of several other investigators,4-8 we believe that twice-daily penicillin V therapy is an effective regimen. The Committee on Infectious Diseases of the American Academy of Pediatrics also notes that "with good compliance, two doses of oral pencillin totaling 800,000 U (500 mg) daily have been reported to be effective."9 SN - 0002-922X M3 - doi: 10.1001/archpedi.1989.02150210013003 UR - http://dx.doi.org/10.1001/archpedi.1989.02150210013003 ER -