TY - JOUR T1 - URine drug screening in mothers and newborns AU - Osterloh JD, Lee BL Y1 - 1989/07/01 N1 - 10.1001/archpedi.1989.02150190041017 JO - American Journal of Diseases of Children SP - 791 EP - 793 VL - 143 IS - 7 N2 - • A retrospective analysis of comprehensive urine drug screening was performed during a 13-month period on specimens submitted from the Neonatal Nursery and Obstetrics/Gynecology wards at San Francisco (Calif) General Hospital (mothers, N = 601; newborns, N =339). Of mothers and newborns, respectively, 19.2% and 15.3% of all admissions during this period were screened; 68.2% and 63.1% of urine samples submitted were positive for any drug; 38.8% and 21.1% of screens were positive for more than one drug; and 45.8% and 41.6% were positive for cocaine. In mother-newborn pairs (N = 191) where urine samples were submitted within 4 days of each other, an 84% concordance was shown for cocaine and 67% for methadone, but concordance was much less for other drugs (<21%). These results indicate that cocaine was the most common drug detectable in the peripartum period and that both mothers and newborns should be tested to confirm the suspicion of drug effect or withdrawal in the newborn.(AJDC. 1989;143:791-793) SN - 0002-922X M3 - doi: 10.1001/archpedi.1989.02150190041017 UR - http://dx.doi.org/10.1001/archpedi.1989.02150190041017 ER -