TY  - JOUR
T1  - VItamin k absorption capacity and its association with vitamin k deficiency
AU  - Shinzawa T, Mura T, Tsunei M, Shiraki K
Y1  - 1989/06/01
N1  - 10.1001/archpedi.1989.02150180064022
JO  - American Journal of Diseases of Children
SP  - 686
EP  - 689
VL  - 143
IS  - 6
N2  - • We measured plasma vitamin K concentrations in 194 5-day-old infants three hours after administration of a 4-mg dose of vitamin K (menaquinone-4, Kaytwo syrup, Eisai Co Ltd, Tokyo, Japan). We investigated association with other factors contributing to vitamin K deficiency. These plasma vitamin K concentrations varied greatly among the neonates from values below the limit of detection (2 ng/mL) to more than 1000 ng/mL. The vitamin K concentration was associated with nutritive vitamin K deficiency represented by plasma protein induced by vitamin K absence or antagonist-II (PIVKA-II) values. The wide variation in vitamin K absorption is considered to be one of the major causative factors in infantile vitamin K deficiency.(AJDC 1989;143:686-689)
SN  - 0002-922X
M3  - doi: 10.1001/archpedi.1989.02150180064022
UR  - http://dx.doi.org/10.1001/archpedi.1989.02150180064022
ER  -