TY - JOUR T1 - Prolactinoma in an adolescent girl: Unusual response to bromocriptine therapy AU - TIWARY CM Y1 - 1989/05/01 N1 - 10.1001/archpedi.1989.02150170015009 JO - American Journal of Diseases of Children SP - 521 EP - 523 VL - 143 IS - 5 N2 - Sir.—Although pituitary tumors have been reported in young children,1 prolactinoma in young girls is rare. The youngest described patient, to my knowledge, was a 13-year-old girl.2 With bromocriptine mesylate therapy, the symptoms of patients with prolactinoma improve and the prolactin level normalizes or is greatly reduced.2-4 Herein, I describe another adolescent girl with prolactinoma, who showed a dissociation of response to bromocriptine, resumption of menses and cessation of galactorrhea, and continued elevation of prolactin levels.Patient Report.—A 15-year-old black girl with cessation of menses for 1 year and galactorrhea for 6 months was referred to the pediatric endocrine clinic of the Walter Reed Army Medical Center, Washington DC, on July 31, 1979. Born July 12, 1964, her growth and development had been unremarkable. Menarche occurred at the age of 13 years (July 1977). Regular menses continued until December 1977 when it became scanty and infrequent and SN - 0002-922X M3 - doi: 10.1001/archpedi.1989.02150170015009 UR - http://dx.doi.org/10.1001/archpedi.1989.02150170015009 ER -