TY  - JOUR
T1  - GAstrointestinal milk intolerance of infancy
AU  - Berezin S, Schwarz SM, Glassman M, Davidian M, Newman LJ
Y1  - 1989/03/01
N1  - 10.1001/archpedi.1989.02150150119029
JO  - American Journal of Diseases of Children
SP  - 361
EP  - 362
VL  - 143
IS  - 3
N2  - • During a period of 30 months, cow's milk–or soy protein–induced colitis was diagnosed in 22 infants. All patients presented with hematochezia. Only three patients had substantial diarrhea. Colonoscopic evaluations demonstrated a characteristic mucosal appearance, manifested by aphthoid ulcerations with intervening, normal-appearing mucosa. Histologic findings included surface ulcerations and associated inflammation of the lamina propria and submucosa, marked by substantial eosinophilic infiltration. Both clinical symptoms and colonoscopic abnormalities rapidly resolved in all patients after the elimination of cow's milk and/or soy protein from the diet. These data indicate that hematochezia may be the predominant symptom of cow's milk protein and soy protein intolerance in many affected infants, and that colonoscopy is the most effective means of establishing a definitive diagnosis in this patient population.(AJDC 1989;143:361-362)
SN  - 0002-922X
M3  - doi: 10.1001/archpedi.1989.02150150119029
UR  - http://dx.doi.org/10.1001/archpedi.1989.02150150119029
ER  -