TY  - JOUR
T1  - PRotein intake and renal function in children
AU  - Nakano M, Alon U, Jennings SS, Chan JM
Y1  - 1989/02/01
N1  - 10.1001/archpedi.1989.02150140046018
JO  - American Journal of Diseases of Children
SP  - 160
EP  - 163
VL  - 143
IS  - 2
N2  - • To evaluate the effects of protein intake on renal tubular functions, seven metabolic studies were performed on five adolescents with mild, chronic renal insufficiency. After equilibration, patients were randomly assigned to two periods of four days each on either a high-protein diet (HPD) or a low-protein diet (LPD), with energy intakes remaining the same during both periods. High protein intake resulted in significantly higher mean (±SD) daily creatinine excretion and clearance rates. The HPD was associated with significantly increased excretion rates of potassium, phosphate, sulfate, and calcium. Net acid excretion with the HPD was nearly threefold higher than that observed with the LPD. These differences were unassociated with urinary pH, which remained similar with both diets. We conclude that different protein intakes affect urinary excretion of creatinine, potassium, phosphate, sulfate, calcium, and net acid.(AJDC 1989;143:160-163)
SN  - 0002-922X
M3  - doi: 10.1001/archpedi.1989.02150140046018
UR  - http://dx.doi.org/10.1001/archpedi.1989.02150140046018
ER  -