TY - JOUR T1 - HYperactivity and medication-reply AU - VARGA JR Y1 - 1979/12/01 N1 - 10.1001/archpedi.1979.02130120079020 JO - American Journal of Diseases of Children SP - 1288 EP - 1288 VL - 133 IS - 12 N2 - In Reply.—I share many of Dr Smith's concerns regarding the use of stimulant medication in children with attentional difficulties. I do believe that he overstates the potential for harm with regard to the long-term cardiovascular effects. The overwhelming majority of follow-up studies do not indicate that this is a major problem area. The work by Sprague and Slater1 suggests that our end points for titrating medication effect may need to differentiate between learning and behavioral phenomena. This is a development that I strongly encourage and have emphasized in the article.It is not my intention or desire to suggest that medication should be the mainstay of therapy. It is helpful for carefully selected children as part of a more comprehensive program that uses educational and behavioral intervention strategies. Rather than reserving its use for situations where "all else fails" as recommended by Dr Smith, I would suggest a SN - 0002-922X M3 - doi: 10.1001/archpedi.1979.02130120079020 UR - http://dx.doi.org/10.1001/archpedi.1979.02130120079020 ER -