TY  - JOUR
T1  - GRam-negative bacillary sepsis associated with use of lipid emulsion in parenteral nutrition
AU  - MCKEE KT, JR, MELLY M, GREENE HL, SCHAFFNER W
Y1  - 1979/06/01
N1  - 10.1001/archpedi.1979.02130060089023
JO  - American Journal of Diseases of Children
SP  - 649
EP  - 650
VL  - 133
IS  - 6
N2  - The use of solutions for parenteral nutrition has greatly enhanced the management of medical and surgical disorders. Two general classes of solutions are employed: total parenteral nutrition solutions (TPN), containing a mixture of amino acids, glucose, electrolytes, and vitamins, and soybean oil emulsion (Intralipid). Both solutions have been shown to support the growth of bacteria and fungi.1,2 Although sepsis is a recognized complication of the use of TPN solutions,2 there have been no reports of infection with the use of lipid emulsion. We report two distinct episodes of lipid emulsion-associated sepsis with two different Gram-negative microorganisms in a chronically ill infant.Report of a Case.—An infant with complications resulting from a midgut volvulus required parenteral nutrition at 3½ months of age and a central venous catheter was inserted. Both glucose-amino acid (TPN) solution and lipid emulsion were administered via a "Y" configuration delivery system. A 0.22-μ particle
SN  - 0002-922X
M3  - doi: 10.1001/archpedi.1979.02130060089023
UR  - http://dx.doi.org/10.1001/archpedi.1979.02130060089023
ER  -