TY  - JOUR
T1  - SIckle cell disease
AU  - PEGELOW C, POWARS D, OVERTURF GD
Y1  - 1979/04/01
N1  - 10.1001/archpedi.1979.02130040102029
JO  - American Journal of Diseases of Children
SP  - 448
EP  - 448
VL  - 133
IS  - 4
N2  - Sir.—A recent Journal report by Buchanan and Glader entitled, "Leukocyte Counts in Children With Sickle Cell Disease" (132:396-398, 1978), concluded in part that "an absolute band count greater than 1,000/μL suggests bacterial infection in children with sickle cell anemia." They found such a level in 14 of 16 episodes of bacterial infection but in only three of 35 episodes of vaso-occlusive crisis.In an attempt to evaluate this finding, we reviewed our experience with 15 episodes of septicemia and ten of meningitis that have been reported in part in a previous communication.1 Cases were selected on the basis of age (younger than 18 years) and a positive bacterial culture of blood or CSF. In addition, we reviewed the records of 30 children hospitalized for painful crisis in whom infection was not considered a contributing factor. The first leukocyte and differential cell count obtained within 24 hours of the
SN  - 0002-922X
M3  - doi: 10.1001/archpedi.1979.02130040102029
UR  - http://dx.doi.org/10.1001/archpedi.1979.02130040102029
ER  -