TY - JOUR T1 - SYstemic group d streptococcal infection in newborn infants AU - Buchino JJ, Ciambarella E, Light I Y1 - 1979/03/01 N1 - 10.1001/archpedi.1979.02130030046007 JO - American Journal of Diseases of Children SP - 270 EP - 273 VL - 133 IS - 3 N2 - • Thirteen cases of group D streptococcal neonatal sepsis and/or meningitis were identified at the Cincinnati Children's Hospital from 1970 to 1976. Ages at onset of disease ranged from 1 to 25 days. The most frequent symptoms were fever (five cases), lethargy (five cases), and respiratory difficulty (four cases). Blood cultures for seven infants were positive; CSF cultures for five infants were positive; and CSF and blood cultures for one infant were both positive. In 12 patients, parenteral antibiotic therapy consisted of a penicillin and an aminoglycoside. One infant with a severe meningomyelocele died. The other 12 infants showed a rapid clinical response with seven patients improving within 48 hours of the start of therapy. Infection with group D streptococcus results in a low-grade systemic disease in both full-term and premature infants that responds favorably to appropriate therapy.(Am J Dis Child 133:270-273, 1979) SN - 0002-922X M3 - doi: 10.1001/archpedi.1979.02130030046007 UR - http://dx.doi.org/10.1001/archpedi.1979.02130030046007 ER -