TY - JOUR T1 - PIcture of the month AU - Gellis SS, Feingold M, Moyer F Y1 - 1969/10/01 N1 - 10.1001/archpedi.1969.02100040587009 JO - American Journal of Diseases of Children SP - 585 EP - 586 VL - 118 IS - 4 N2 - Denouement and Discussion  Potter's SyndromeManifestations  Major manifestations include renal agenesis and a characteristic facial appearance. The patients are small for dates infants who die soon after birth. Breech presentation and oligohydramnios are common, and scattered over the placenta and membranes are yellow nodular accumulations of vernix cells (amnion nodosum). The oligohydramnios is felt to be partially responsible for failure of normal lung development.The face is flattened and appears prematurely old. The eyes are widely spaced with epicanthal folds and a crease below the lower lids. Characteristically, the nose is flattened and the ears are large, low set, posteriorly placed, floppy, and easily folded because of a deficiency of cartilage. Micrognathia is prominent and a skin crease is often noted on the chin. The kidneys and frequently the ureters are absent or rudimentary, and the uterus and vagina may also be missing. Pulmonary hypoplasia is found in SN - 0002-922X M3 - doi: 10.1001/archpedi.1969.02100040587009 UR - http://dx.doi.org/10.1001/archpedi.1969.02100040587009 ER -