TY  - JOUR
T1  - PIcture of the month
AU  - Gellis SS, Feingold M
Y1  - 1969/06/01
N1  - 10.1001/archpedi.1969.02100030701014
JO  - American Journal of Diseases of Children
SP  - 699
EP  - 700
VL  - 117
IS  - 6
N2  - Denouement and Discussion 
    Cri Du Chat Syndrome 
    (Cry of the Cat Syndrome)Manifestations 
    The major manifestations include severe mental/motor retardation, microcephaly, rounded facies, ocular hypertelorism, and a cat-like cry. These children are usually small for dates infants who do not thrive. The abnormal cry, present at birth, may be caused by a small larynx, or a larynx which is abnormal in shape or position. The cry remains cat-like for varying periods of time, and, as the infant grows older, it may lose its characteristic quality yet continue to sound abnormal. In addition to the prominent ocular hypertelorism there may be an antimongoloid slant to the eyes, epicanthal folds, strabismus, and optic atrophy. The ears may be low set or prominent or both. Micrognathia and occasionally cleft palate are present. There are various types of congenital heart defects. The retardation is usually severe, and hypotonia may be found in the 

SN  - 0002-922X
M3  - doi: 10.1001/archpedi.1969.02100030701014
UR  - http://dx.doi.org/10.1001/archpedi.1969.02100030701014
ER  -