TY  - JOUR
T1  - STudies on the brain ganglioside strandin in normal brain and in tay-sachs' disease
AU  - FOLCH-PI J, LEES M
Y1  - 1959/05/01
N1  - 10.1001/archpedi.1959.02070010732012
JO  - A.M.A. Journal of Diseases of Children
SP  - 730
EP  - 738
VL  - 97
IS  - 5_PART_II
N2  - Since our results bearing directly on TaySachs' disease are few and mainly of a confirmatory nature, it would seem that the best contribution that we can make to this Symposium is to report in some detail our own work on the brain ganglioside, strandin. This will constitute the bulk of the discussion and will be followed by the presentation of the results of the analyses of two brains of patients with Tay-Sachs' disease.Strandin1 was reported originally as a complex lipide which had been isolated from gray matter by three different methods. Its name was chosen because, when recovered from water solutions by drying, strandin was obtained as a residue of long, glistening, birefringent strands. It was readily soluble in water as an undialyzable solute which was homogeneous in the electrophoretic field over a wide pH range. By ultracentrifugation it showed a major component which accounted for 80% of
SN  - 0096-6916
M3  - doi: 10.1001/archpedi.1959.02070010732012
UR  - http://dx.doi.org/10.1001/archpedi.1959.02070010732012
ER  -