TY  - JOUR
T1  - ONe-year surveillance of methicillin-resistant staphylococcus aureus nasal colonization and skin and soft tissue infections in collegiate athletes
AU  - Creech C, Saye E, McKenna BD, et al
Y1  - 2010/07/01
N1  - 10.1001/archpediatrics.2010.93
JO  - Archives of Pediatrics & Adolescent Medicine
SP  - 615
EP  - 620
VL  - 164
IS  - 7
N2  - Objective 
    To determine the frequency and clinical importance of methicillin-resistant Staphylococcus aureus (MRSA) colonization in student athletes.Design 
    Prospective observational cohort study.Setting 
    A major university in the southeastern United States.Participants 
    Student athletes participating in the men's football and women's lacrosse programs (N = 126).Main Exposure 
    Monthly assessment of S aureus nasal colonization.Main Outcome Measures 
    Trends in S aureus colonization over time and the occurrence of skin and soft tissue infections.Results 
    Methicillin-resistant S aureus nasal colonization varied significantly through the athletic season (4%-23%), peaking during times of highest athletic activity. This increase in colonization was not associated with the development of an outbreak of skin and soft tissue infections, and no single MRSA clone emerged as a dominant isolate.Conclusions 
    During the athletic season, there is a considerable burden of MRSA colonization in student athletes; however, colonization alone appears to be insufficient to trigger an outbreak of staphylococcal infections. A combination of distinct molecular characteristics in the organism and specific host factors may govern the development of staphylococcal disease.
SN  - 1072-4710
M3  - doi: 10.1001/archpediatrics.2010.93
UR  - http://dx.doi.org/10.1001/archpediatrics.2010.93
ER  -