TY - JOUR T1 - INtegrating past research on related abstinence and safer-sex interventions—reply AU - Jemmott JB, III, Jemmott LS, Stevens R Y1 - 2010/07/01 N1 - 10.1001/archpediatrics.2010.121 JO - Archives of Pediatrics & Adolescent Medicine SP - 679 EP - 681 VL - 164 IS - 7 N2 - We are grateful for the kind comments of Underhill et al and Dr Tevendale regarding our article1 reporting significant effects of a theory-based abstinence-only intervention in delaying sexual initiation among African American adolescents. We randomly allocated participants to 5 interventions; therefore, pairwise comparisons involved only 40% of participants. This provided adequate statistical power to detect differences between each of the 4 human immunodeficiency virus (HIV)/sexually transmitted disease (STD) risk reduction interventions and the control group, but much less power for pairwise comparisons among the 4 HIV/STD interventions because the anticipated effect size was much smaller. Our article benefited from the rigorous review process that helps improve the quality of published trials and used an improved analytic approach compared with our presentation.2 We regarded the 4 comparisons between the HIV/STD interventions and control as primary and additional pairwise comparisons as post hoc to reduce type 1 errors that increase with multiple comparisons. SN - 1072-4710 M3 - doi: 10.1001/archpediatrics.2010.121 UR - http://dx.doi.org/10.1001/archpediatrics.2010.121 ER -