TY  - JOUR
T1  - BOdy mass index and timing of pubertal initiation in boys
AU  - Lee JM, Kaciroti N, Appugliese D, Corwyn RF, Bradley RH, Lumeng JC
Y1  - 2010/02/01
N1  - 10.1001/archpediatrics.2009.258
JO  - Archives of Pediatrics & Adolescent Medicine
SP  - 139
EP  - 144
VL  - 164
IS  - 2
N2  - Objective 
    To examine the association between body mass index (BMI [calculated as weight in kilograms divided by height in meters squared]) and timing of pubertal onset in a population-based sample of US boys.Design 
    Longitudinal prospective study.Setting 
    Ten US sites that participated in the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development.Participants 
    Of 705 boys initially enrolled in the study, information about height and weight measures and pubertal stage by age 11.5 years was available for 401 boys.Main Exposure 
    The BMI trajectory created from measured heights and weights at ages 2, 3, 4.5, 7, 9, 9.5, 10.5, and 11.5 years.Main Outcome Measure 
    Onset of puberty at age 11.5 years as measured by Tanner genitalia staging.Results 
    Boys in the highest BMI trajectory (mean BMI z score at age 11.5 years, 1.84) had a greater relative risk of being prepubertal compared with boys in the lowest BMI trajectory (mean BMI z score at age 11.5 years, −0.76) (adjusted relative risk = 2.63; 95% confidence interval, 1.05-6.61; P = .04).Conclusions 
    The relationship between body fat and timing of pubertal onset is not the same in boys as it is in girls. Further studies are needed to better understand the physiological link between body fat and timing of pubertal onset in both sexes.
SN  - 1072-4710
M3  - doi: 10.1001/archpediatrics.2009.258
UR  - http://dx.doi.org/10.1001/archpediatrics.2009.258
ER  -