TY - JOUR T1 - NEcessary innovations in immunization delivery AU - Davis MM, Shah SS Y1 - 2009/05/04 N1 - 10.1001/archpediatrics.2009.72 JO - Archives of Pediatrics & Adolescent Medicine SP - 483 EP - 485 VL - 163 IS - 5 N2 - Nevertheless, childhood vaccination in the 21st century faces multiple challenges that threaten its success. An increasingly skeptical public questions whether vaccines are safe enough, leading to underimmunization of large segments of the population in some regions. Periodic vaccine shortages necessitate prioritizing vaccines for the highest-risk populations, leading to delayed immunization of many young children. Waning immunity and low vaccination rates among adults leave the most vulnerable children underprotected against some vaccine-preventable diseases, leading to communitywide outbreaks of infections such as pertussis. Lastly, newly recommended vaccines for adolescents are targeted to a population renowned for low health care use rates. SN - 1072-4710 M3 - doi: 10.1001/archpediatrics.2009.72 UR - http://dx.doi.org/10.1001/archpediatrics.2009.72 ER -