TY - JOUR T1 - HEart disease screening of schoolchildren in taiwan AU - Yu C, Lue H, Wu S, Chen M Y1 - 2009/03/02 N1 - 10.1001/archpediatrics.2008.562 JO - Archives of Pediatrics & Adolescent Medicine SP - 233 EP - 237 VL - 163 IS - 3 N2 - Objective  To evaluate the sensitivity of a heart disease screening program for schoolchildren.Design  Prospective cohort study.Setting  Taitung County, Taiwan.Participants  All first- and fourth-grade elementary school students and first-year junior high school students screened between September 1, 2005, and June 30, 2007.Intervention  A 2-level heart disease screening program was undertaken. Level 1 screening included a history questionnaire and phonocardiography and electrocardiography. Level 2 screening consisted of examination by a pediatric cardiologist of all children who had abnormal findings on level 1 screening. A control group comprised children whose level 1 screening results were normal. Children with abnormalities on level 2 screening were referred for a detailed cardiac evaluation.Main Outcome Measures  Previously unsuspected heart diseases.Results  Of 25 816 children undergoing the level 1 screening program, 5330 had positive findings, of whom 5235 underwent level 2 screening, along with 1104 children in the control group. The pediatric cardiologist referred 780 children to the hospital for full evaluation, including 18 controls and 114 patients with a previous diagnosis of heart disease. A total of 292 children, including 2 controls, had evidence of heart disease, which was previously unsuspected in 178 (61.0%). Excluding children with a previous diagnosis of heart disease, the sensitivity of the screening program was 82.6%. The specificity and the positive predictive value were 98.3% and 28.6%, respectively.Conclusion  The 2-level heart disease screening program has good sensitivity and detects asymptomatic but potentially life-threatening heart disease in some children. SN - 1072-4710 M3 - doi: 10.1001/archpediatrics.2008.562 UR - http://dx.doi.org/10.1001/archpediatrics.2008.562 ER -