TY - JOUR T1 - ELevated circulating estradiol level in neonatal ovarian cyst AU - Arisaka O, Kanazawa S, Ohyama M, Nitta A, Suzumura H, Kuribayashi T Y1 - 1999/11/01 N1 - JO - Archives of Pediatrics & Adolescent Medicine SP - 1202 EP - 1203 VL - 153 IS - 11 N2 - During the past few years we encountered 5 patients with OC who were given the diagnosis prenatally, which allowed us to measure their circulating levels of estradiol (E2) serially after birth. Two of the 5 patients who had unilateral large cysts (5 cm in diameter) underwent periodic ultrasound-guided percutaneous cyst aspiration for prevention of ovarian torsion until 1 month of age; the E2 level of the cystic fluid was 9200 pmol/L and 25,100 pmol/L, respectively. The remaining 3 patients who had unilateral or bilateral cysts (each 2-4 cm in diameter) were observed conservatively by carrying out serial ultrasonography. Subsequently, all the cysts showed spontaneous resolution at around 6 months of age. The changes in the circulating levels of E2 in these 5 patients are illustrated in Figure 1. SN - 1072-4710 M3 - doi: UR - http://dx.doi.org/ ER -