TY  - JOUR
T1  - ASsociation of depression and anxiety disorders with weight change in a prospective community-based study of children followed up into adulthood
AU  - Anderson SE, Cohen P, Naumova EN, Must A
Y1  - 2006/03/01
N1  - 10.1001/archpedi.160.3.285
JO  - Archives of Pediatrics & Adolescent Medicine
SP  - 285
EP  - 291
VL  - 160
IS  - 3
N2  - Objective 
    To investigate childhood to adulthood weight change associated with anxiety and depression.Design 
    The Children in the Community Study. A prospective longitudinal investigation.Setting 
    Albany and Saratoga Counties, New York.Participants 
    Eight hundred twenty individuals (403 females and 417 males) assessed at 4 time points: in 1983 when they were 9 to 18 years old (n = 776), in 1985 to 1986 when they were 11 to 22 years old (n = 775), in 1991 to 1994 when they were 17 to 28 years old (n = 776), and in 2001 to 2003 when they were 28 to 40 years old (n = 661).Main Exposures 
    Anxiety disorders and depression assessed by structured diagnostic interview.Main Outcome Measures 
    Centers for Disease Control and Prevention body mass index z score (BMIz), a measure of weight status; and association of anxiety and depression with BMIz level and annual change.Results 
    In females, anxiety disorders were associated with higher weight status, a BMIz of 0.13 (95% confidence interval, 0.01-0.25) units higher compared with females without anxiety disorders. Female depression was associated with a gain in BMIz of 0.09 units/y (95% confidence interval, 0.03-0.15 units/y), modified by the age when depression was first observed, such that early depression onset was associated with a higher subsequent BMIz than depression onset at older ages. In males, childhood depression was associated with a lower BMIz (−0.46; 95% confidence interval, −0.93 to 0.02 units lower at the age of 9 years), but BMIz trajectories for males with or without depression converged in adulthood; male anxiety disorders were not substantively associated with weight status.Conclusions 
    Anxiety disorders and depression were associated with a higher BMIz in females, whereas these disorders in males were not associated with a higher BMIz. These results, if causal and confirmed in other prospective studies, support treating female anxiety and depression as part of comprehensive obesity prevention efforts.
SN  - 1072-4710
M3  - doi: 10.1001/archpedi.160.3.285
UR  - http://dx.doi.org/10.1001/archpedi.160.3.285
ER  -