TY - JOUR T1 - SImulating cost-effectiveness of fluoride varnish during well-child visits for medicaid-enrolled children AU - Quiñonez RB, Stearns SC, Talekar BS, Rozier R, Downs SM Y1 - 2006/02/01 N1 - 10.1001/archpedi.160.2.164 JO - Archives of Pediatrics & Adolescent Medicine SP - 164 EP - 170 VL - 160 IS - 2 N2 - Objective  To examine the cost-effectiveness of fluoride varnish application by medical providers when implemented within a well-child periodicity schedule for Medicaid-enrolled children.Design  Cost-effectiveness was analyzed using published probabilities and costs. Input parameters included the effectiveness of fluoride varnish (35.4%) applied according to the well-child periodicity schedule up to 3 years of age at $16.00 per application, annual caries increment (14%), age-specific dental care usage rates (0.2% at 9 months to 19% at 42 months), and age-related nonhospital treatment costs ($292.00-$503.00) and hospital treatment costs ($2191.00-$2940.00). Sensitivity analysis was conducted to assess the effects for varying input parameters.Setting  Well-child visits during primary care.Participants  Children aged 9 to 42 months.Intervention  Application of universal fluoride varnish (fluoride varnish—all) at 9, 18, 24, and 36 months vs no intervention (fluoride varnish—none) was compared.Main Outcome Measures  Cost per month without cavities and treatment averted during the first 42 months of life from a Medicaid payer's perspective.Results  Fluoride varnish improved clinical outcomes by 1.52 cavity-free months but at a cost of $7.18 for each cavity-free month gained per child and $203 for each treatment averted. Considerable uncertainty existed for some parameters. Fluoride varnish was cost saving when dental services and nonhospital treatment costs were 1.5 to 2 times greater, respectively, than our base case estimate.Conclusions  Based on these assumptions, fluoride varnish use in the medical setting is effective in reducing early childhood caries in low-income populations but is not cost saving in the first 42 months of life. Potential total cost reductions with varying parameters suggest that evaluations using a longitudinal cohort are needed. SN - 1072-4710 M3 - doi: 10.1001/archpedi.160.2.164 UR - http://dx.doi.org/10.1001/archpedi.160.2.164 ER -