TY  - JOUR
T1  - Genetic risk in childhood obesity: Implications for clinical practice
AU  - Young RP, Hopkins RJ
Y1  - 2013/02/01
N1  - 10.1001/2013.jamapediatrics.252
JO  - JAMA Pediatrics
SP  - 196
EP  - 198
VL  - 167
IS  - 2
N2  - 
First, given the steeply rising rates of obesity over the last few decades, it is clear that changes in lifestyle (ie, the environment) are “pivotal” to the development of obesity.1 While the genes underlying obesity have been present for centuries, it is their effect that has recently emerged in societies where “lifestyle” has dramatically changed. This means regardless of genetic predisposition, there need be no concern about “genetic determinism” in the public health community. Instead there should be enthusiasm for the potential to identify those at greatest risk for targeted and cost-effective interventions. This must be preferable to (over)generalized health messages that are inconsequential for the wider population. The best example of the success of the targeted approach comes from the enormous drop in death rates from coronary artery disease following several decades of cholesterol-lowering treatment (see later).

SN  - 2168-6203
M3  - doi: 10.1001/2013.jamapediatrics.252
UR  - http://dx.doi.org/10.1001/2013.jamapediatrics.252
ER  -