TY - JOUR T1 - SChool-based health center use and high school dropout rates—reply AU - Kerns SU, Pullmann MD, Walker S, Lyon AR, Cosgrove TJ, Bruns EJ Y1 - 2012/07/01 N1 - 10.1001/archpediatrics.2012.553 JO - Archives of Pediatrics & Adolescent Medicine SP - 675 EP - 677 VL - 166 IS - 7 N2 - Treating time-varying variables as fixed can result in a systematic bias referred to as “time-dependent bias,”1 “immortal time bias,”2 or “survival bias.”3 This is a common analytic error; in a review of publications from 9 top medical journals from 1998 to 2002, of 127 studies that used survival analysis with time-dependent variables, 41% (52 studies) were susceptible to time-dependent bias because they did not appropriately operationalize at least 1 time-varying variable in the model.1 SN - 1072-4710 M3 - doi: 10.1001/archpediatrics.2012.553 UR - http://dx.doi.org/10.1001/archpediatrics.2012.553 ER -