TY  - JOUR
T1  - NEphrolithiasis with renal tubular failure
AU  - ISRAELS S, MUTH HH, ZEAVIN II
Y1  - 1949/09/01
N1  - 10.1001/archpedi.1949.02030050402012
JO  - American Journal of Diseases of Children
SP  - 389
EP  - 392
VL  - 78
IS  - 3
N2  - FAILURE of a single function of the renal tubules has been a well recognized entity. Thus, Thorn and his associates1 reported a case of "salt-losing nephritis" which so closely simulated adrenocortical hypofunction (Addison's disease) that it went unrecognized for some time. Albright and his co-workers2 gathered together and reported 9 cases of nephrolithiasis and nephrocalcinosis in which they showed that the primary defect lay in the inability of the renal tubules to form ammonia. This resulted in the loss of fixed base, with precipitation of calcium salts in the tubules and renal pelves. Loss of fixed base other than calcium may occur; potassium deficiency with resulting paralysis has been reported by Brown, Currens and Marchand3 in a case of chronic nephritis in which tubular formation of ammonia had failed.The case presented herein shows many of the features of those described by Albright and his associates.REPORT 
    
SN  - 0096-8994
M3  - doi: 10.1001/archpedi.1949.02030050402012
UR  - http://dx.doi.org/10.1001/archpedi.1949.02030050402012
ER  -