TY  - JOUR
T1  - PReparation of sodium bicarbonate for intraperitoneal use
AU  - SHOHL AT
Y1  - 1929/11/01
N1  - 10.1001/archpedi.1929.01930110026003
JO  - American Journal of Diseases of Children
SP  - 927
EP  - 928
VL  - 38
IS  - 5
N2  - Sodium bicarbonate has been the alkali of choice for combating acidosis, especially for parenteral injection. The difficulty of sterilizing it is one of the main objections to its use. Palmer1 stated that sodium bicarbonate, after being boiled for ten minutes or autoclaved at 20 pounds (9 Kg.) pressure for fifteen minutes, is still suitable for administration intravenously. By such procedures, carbon dioxide is lost and sodium carbonate formed. The solution is rendered alkaline.Marriott and Hartmann,2 in a recent article, recommended a solution of sodium bicarbonate for intraperitoneal use. They did not state the concentration used. They prepared soda by first boiling a solution and then reintroducing carbon dioxide in the presence of phenol red until the reaction was ph 7.4. This had to be done with sterile precautions.I have found that the acidity of a solution of sodium bicarbonate may be first adjusted with carbon
SN  - 0096-8994
M3  - doi: 10.1001/archpedi.1929.01930110026003
UR  - http://dx.doi.org/10.1001/archpedi.1929.01930110026003
ER  -