TY - JOUR T1 - Nutrient supplementation and neurodevelopment: Timing is the key AU - Cusick SE, Georgieff MK Y1 - 2012/05/01 N1 - 10.1001/archpediatrics.2012.199 JO - Archives of Pediatrics & Adolescent Medicine SP - 481 EP - 482 VL - 166 IS - 5 N2 - The human brain develops throughout a person's life span and is dependent on an adequate supply of nutrients to support its development.1 One of the most rapid periods of overall brain growth occurs during the last trimester in the fetus through the first 3 postnatal years.2 Thus, there is a major public health emphasis on promoting nutritional adequacy during these formative years in order to optimize developmental outcome. The brain, however, is not a homogenous organ with respect to its development. Individual brain regions (eg, the hippocampus and the prefrontal cortex) and processes (eg, myelination) exhibit variable trajectories with respect to the timing of the onset of development and the speed of development.2 SN - 1072-4710 M3 - doi: 10.1001/archpediatrics.2012.199 UR - http://dx.doi.org/10.1001/archpediatrics.2012.199 ER -