TY  - JOUR
T1  - REliable change in postconcussive symptoms and its functional consequences among children with mild traumatic brain injury
AU  - Yeates K, Kaizar E, Rusin J, et al
Y1  - 2012/07/01
N1  - 10.1001/archpediatrics.2011.1082
JO  - Archives of Pediatrics & Adolescent Medicine
SP  - 615
EP  - 622
VL  - 166
IS  - 7
N2  - Objective 
                  To examine reliable change in postconcussive symptoms and its functional consequences among children with mild traumatic brain injury (TBI) over the first year postinjury as compared with children with orthopedic injuries.Design 
                  Prospective, longitudinal cohort.Setting 
                  Emergency departments at 2 children's hospitals.Participants 
                  Eight- to 15-year-old children with mild TBI (n = 186) or orthopedic injuries (n = 99).Main Exposure 
                  Closed-head or orthopedic trauma.Main Outcome Measures 
                  Parents rated preinjury symptoms retrospectively shortly after injury and postconcussive symptoms at 2 weeks and 3 and 12 months postinjury. A regression-based approach was used to determine whether each child displayed reliable increases in postconcussive symptoms at each postinjury occasion. Health-related quality of life was assessed at 3 and 12 months postinjury. Information regarding children's educational programming was collected at the initial and 12-month assessments.Results 
                  Children with mild TBI were significantly more likely than those with orthopedic injuries to show reliable increases in both cognitive and somatic symptoms. Group differences in the likelihood of reliable increases became less common with time for somatic symptoms but persisted to 12 months postinjury for cognitive symptoms. Among children with mild TBI, reliable increases in symptoms were more common among children with loss of consciousness or abnormalities on neuroimaging. Reliable increases in symptoms were associated with significant declines in health-related quality of life and an increased likelihood of educational intervention.Conclusion 
                  Many children with mild TBI show reliable increases in postconcussive symptoms that are associated with significant functional impairment in their daily lives.
SN  - 1072-4710
M3  - doi: 10.1001/archpediatrics.2011.1082
UR  - http://dx.doi.org/10.1001/archpediatrics.2011.1082
ER  -