RT Journal A1 Ivarsson SA, Ericsson U, Fredriksson B, Persson PH T1 ULtrasonic imaging in the differential diagnosis of diffuse thyroid disorders in children JF American Journal of Diseases of Children JO American Journal of Diseases of Children YR 1989 FD November 1 VO 143 IS 11 SP 1369 OP 1372 DO 10.1001/archpedi.1989.02150230127041 UL http://dx.doi.org/10.1001/archpedi.1989.02150230127041 AB • In 22 patients with suspected diffuse goiter, the diagnostic accuracy of ultrasonography was compared with that of aspiration biopsy cytology and thyroid antibody testing. Ultrasonography was abnormal in 100% (10/10) of the patients with autoimmune thyroid disease, only 90% (9/10) of whom were identified with antibody testing. All patients with diffuse colloid goiter had normal echo patterns on ultrasound imaging, whereas 29% (2/7) of them had positive results on antibody testing. Whether these are 'false positives' or represent focal thyroiditis remains unclear. Thus, ultrasound imaging stands out as a valuable diagnostic tool for the differential diagnosis of diffuse thyroid disorders in children.(AJDC. 1989;143:1369-1372)