RT Journal
A1 Spadoni G, Cianfarani S, Bernardini S, Fabrizio V, Galasso C, Boscherini B
T1 GRowth hormone treatment in children with sporadic primary microcephaly
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1989
FD November 1
VO 143
IS 11
SP 1282
OP 1283
DO 10.1001/archpedi.1989.02150230040019
UL http://dx.doi.org/10.1001/archpedi.1989.02150230040019
AB • Four children with sporadic primary microcephaly associated with short stature, delayed bone age, and low growth velocity are described. All of the children showed a normal growth hormone response to standard pharmacological tests but one of the patients had a reduced spontaneous growth hormone nocturnal secretion. Regardless of the results of their somatotropic function evaluation, the patients were treated with exogenous growth hormone and all of them showed an increase in growth rate.(AJDC. 1989;143:1282-1283)