RT Journal A1 Naeye RL, Peters EC, Bartholomew M, Landis J T1 ORigins of cerebral palsy JF American Journal of Diseases of Children JO American Journal of Diseases of Children YR 1989 FD October 1 VO 143 IS 10 SP 1154 OP 1161 DO 10.1001/archpedi.1989.02150220044018 UL http://dx.doi.org/10.1001/archpedi.1989.02150220044018 AB • Analyses were undertaken to determine the causes of cerebral palsy in a prospective study of 43 437 full-term children. Presumed causes were found for about 71% of the 34 quadriplegic and 40% of the 116 nonquadriplegic patients with cerebral palsy. Risk estimates based on predictive models, adjusted for multiple factors, suggest that 53% of the quadriplegic patients with cerebral palsy could be attributed to congenital disorders, 14% to birth asphyxia, and 8% to other identified disorders. Thirty-five percent of the nonquadriplegic patients with cerebral palsy could be attributed to congenital disorders and 6% to other disorders. In the victims of cerebral palsy, characteristic consequences of birth asphyxia were more often the result of nonasphyxial disorders. These included meconium in the amniotic fluid, low 10-minute Apgar scores, neonatal apnea spells, seizures, persisting neurologic abnormalities, and slow head growth after birth.(AJDC. 1989;143:1154-1161)