RT Journal
A1 Lavoie A, Rottem M, Grodofsky MP, Douglas SD
T1 ANti-staphylococcus aureus ige antibodies for diagnosis of hyperimmunoglobulinemia e-recurrent infection syndrome in infancy
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1989
FD September 1
VO 143
IS 9
SP 1038
OP 1041
DO 10.1001/archpedi.1989.02150210064021
UL http://dx.doi.org/10.1001/archpedi.1989.02150210064021
AB • Four infants with hyperimmunoglobulinemia E presented with a persistent papulovesicular rash and eosinophilia. Serum IgE levels and specific anti-Staphylococcus aureus IgE antibodies were studied during the first year of life. Increased anti-S aureus IgE antibodies were an early indicator of the disease; they appeared as soon as 7 weeks of age in patient 1 and before 1 year of age for the other patients. These antibodies were detected before the development of deeper staphylococcal infections. Prompt diagnosis and treatment are important, as they may prevent long-term infectious complications.(AJDC. 1989;143:1038-1041)