RT Journal
A1 Baliga R, Fleischmann LE, Chang C, Sarnaik AP, Bidani AK, Arcinue EL
T1 ACute renal failure in reye's syndrome
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1979
FD October 1
VO 133
IS 10
SP 1009
OP 1013
DO 10.1001/archpedi.1979.02130100033006
UL http://dx.doi.org/10.1001/archpedi.1979.02130100033006
AB • Three patients with initial clinical manifestations and biochemical findings suggestive of a diagnosis of Reye's syndrome had acute renal insufficiency develop and had evidence of consumptive coagulopathy, not generally considered features of the syndrome. As a group, they could not be distinguished, either on the basis of their clinical manifestations or liver pathologic findings, from the 17 patients with Reye's syndrome without renal failure seen in our institution during the same period of time. The use of osmotic diuretics in an effort to decrease cerebral edema may be life threatening in these patients with compromised renal function since hypervolemia, cardiac failure, and worsening of cerebral edema may occur.(Am J Dis Child 133:1009-1013, 1979)