RT Journal
A1 Ettinger LJ, Freeman AI
T1 HEpatoma in a child with neurofibromatosis
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1979
FD May 1
VO 133
IS 5
SP 528
OP 531
DO 10.1001/archpedi.1979.02130050072015
UL http://dx.doi.org/10.1001/archpedi.1979.02130050072015
AB • A 6-year-old girl had neurofibromatosis and hepatocellular carcinoma (hepatoma). Although neurofibromatosis is a common disorder, hepatic cancers are rare in childhood. Hepatic cancer, Wilms' tumor, and adrenocortical neoplasia are all seen with increased frequency in association with certain congenital anomalies, particularly with hemihypertrophy and various hamartomas. Neurofibromatosis, a hamartomatous disorder, is also seen with these congenital anomalies and it is reported with an unusually high incidence in patients with Wilms' tumor. We therefore suggest that these disorders may be related.(Am J Dis Child 133:528-531, 1979)