RT Journal
A1 Kappy MS, Lightner ES
T1 LOw-dose intravenous insulin in the treatment of diabetic ketoacidosis
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1979
FD May 1
VO 133
IS 5
SP 523
OP 525
DO 10.1001/archpedi.1979.02130050067013
UL http://dx.doi.org/10.1001/archpedi.1979.02130050067013
AB • Continuous slow intravenous infusion of insulin was used in 52 episodes of diabetic ketoacidosis. No complications of therapy, ie, hypoglycemia, induced hypokalemia, insulin resistance, or cerebral edema, were encountered. Potassium phosphate was given to 47 of the 52 patients. Sodium bicarbonate was administered to only one patient. The hyperglycemia frequently resolved more rapidly than the systemic acidosis; this was managed by adding glucose to the intravenous fluids when the blood sugar concentration decreased to approximately 250 mg\dL; insulin infusion, however, was continued until the acidosis was corrected (venous standard bicarbonate > 14 mg/L). We have found this method of treatment to be safe and simple to administer, and we believe it is the preferred treatment of patients with diabetic ketoacidosis.(Am J Dis Child 133:523-525, 1979)