RT Journal
A1 Khodr GS, Cadena GD, Ong TC, Siler-Khodr TM
T1 Y-autosome translocation, gonadal dysgenesis, and gonadoblastoma
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1979
FD March 1
VO 133
IS 3
SP 277
OP 282
DO 10.1001/archpedi.1979.02130030053009
UL http://dx.doi.org/10.1001/archpedi.1979.02130030053009
AB • A 5-year-old girl was discovered to have an abnormal karyotype with a translocation involving the Y chromosome. The primary complaint was slight physical growth retardation. Cytogenetic and endocrinologic evaluations were performed. The chromosomal complement exhibited a mosaicism: 45,X,t(Y;18)(q11;p11)/45,X0. The gonads of this patient were typical streaks containing no ova or follicles. A gonadoblastoma was present bilaterally.(Am J Dis Child 133:277-282, 1979)