RT Journal
A1 SZALAY G
T1 FAmilial pyloric atresia
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1979
FD February 1
VO 133
IS 2
SP 221
OP 221
DO 10.1001/archpedi.1979.02130020113026
UL http://dx.doi.org/10.1001/archpedi.1979.02130020113026
AB Sir.—Konvolinka and Steward (Am J Dis Child 132:903-905, 1978) describe a patient with pyloric atresia and report 81 cases in the medical literature. Although they do not discuss the possible recurrence in siblings, Tan and Murugasu1 (authors' reference 24) considered their report of affected siblings the first in the literature. Actually, there are at least five other families,2 leading the authors of one article3 to suggest the condition is inherited in an autosomal recessive manner. Presumably, α-fetoprotein levels would be elevated in the amniotic fluid of succeeding affected siblings, which suggests the possibility of prenatal diagnosis.4