RT Journal
A1 Woods WG, Corman Luban NL, Hilgartner MW, Miller DR
T1 DIsseminated intravascular coagulation in the newborn
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1979
FD January 1
VO 133
IS 1
SP 44
OP 46
DO 10.1001/archpedi.1979.02130010050008
UL http://dx.doi.org/10.1001/archpedi.1979.02130010050008
AB • We have reviewed 53 cases of disseminated intravascular coagulation (DIC) in the newborn, including 29 cases that were confirmed at autopsy. Factors predisposing to DIC included maternal complications (60%), low Apgar scores (30%), hyaline membrane disease (62%), and sepsis (26%). Diagnostic criteria common to autopsy-proved cases included presence of fibrin degradation products, low factor V activity, a prolonged prothrombin time, and a prolonged partial thromboplastin time and/or thrombocytopenia. There appeared to be no difference in coagulation response or in mortality among patients treated with different therapeutic regimens. Survivors were older gestationally, had higher birth weights, and higher Apgar scores.(Am J Dis Child 133:44-46, 1979)