RT Journal
A1 Gellis SS, Feingold M, Beighton P
T1 PIcture of the month
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1969
FD December 1
VO 118
IS 6
SP 891
OP 892
DO 10.1001/archpedi.1969.02100040893013
UL http://dx.doi.org/10.1001/archpedi.1969.02100040893013
AB Denouement and Discussion 
    Ehlers-Danlos SyndromeManifestations 
    The major manifestations of this syndrome are articular hypermobility, hyperelastic skin, and a tendency to lacerations on relatively minor trauma. Over the bony prominences may be found wide "cigarette paper" scars and fleshy "molluscoid pseudotumors." A bleeding diathesis, of variable severity, is frequently present, and hemorrhage and hematoma formation may occur. Numerous small, hard, subcutaneous nodules are often palpable under the skin, especially over the knees, shins, and forearms. These are calcified and can be demonstrated radiographically, constituting a characteristic feature of the condition.Inguinal and umbilical hernias are common and orthopedic abnormalities, including joint effusions, flat feet, dislocation of joints, and genu recurvatum are frequently encountered. Ocular abnormalities include ease in everting the upper lid, strabismus, and epicanthal folds. Dissecting aneurysm of the aorta, rupture of peripheral arteries, and spontaneous perforation of the intestine are rare but potentially lethal complica