RT Journal
A1 Lascari AD, Hoak JC, Taylor JC, Zellweger H
T1 CHristmas disease in a girl
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1969
FD May 1
VO 117
IS 5
SP 585
OP 588
DO 10.1001/archpedi.1969.02100030587016
UL http://dx.doi.org/10.1001/archpedi.1969.02100030587016
AB IN THE majority of affected families the inheritance of Christmas disease (hemophilia B) is of the same X-linked recessive pattern as true hemophilia (hemophilia A), resulting in a transmission of the disease to men by apparently healthy female carriers. In a small number of instances, however, carriers of the Christmas disease gene have been reported with bleeding symptoms. This report describes Christmas disease in an 11-year-old girl and is the second reported case in which hemarthrosis was observed in a female carrier.Report of a Case 
    An 11-year-old white girl had her first episode of excessive bleeding at the age of 2 years when she bled for one week from a scalp laceration which had been cauterized and sutured. At 5 years she bled for two weeks following a tooth extraction despite plasma infusions. At 8 years of age she bit her tongue and again bled for two weeks in