RT Journal
A1 Ott JE, Robinson A
T1 CErebral gigantism
JF American Journal of Diseases of Children
JO American Journal of Diseases of Children
YR 1969
FD March 1
VO 117
IS 3
SP 357
OP 368
DO 10.1001/archpedi.1969.02100030359023
UL http://dx.doi.org/10.1001/archpedi.1969.02100030359023
AB SINCE Sotos et al1 described the syndrome of cerebral gigantism characterized by large stature, typical facies, nonprogressive neurological disorder, and mental retardation, there have been 33 cases reported.2-10 The purpose of this paper is to present an additional case report which includes some studies not previously emphasized, and to review the literature.Report of a Case 
    The patient is an 11½-year-old white girl who has been evaluated annually since her fifth year because of her large stature. Following a term pregnancy complicated by hyperemesis gravidarum, vaginal bleeding, marked edema, and a difficult six-hour labor, normal deliver ensued. There were no neonatal difficulties except moderate jaundice which persisted for one month. At birth, her measurements were as follows: length, 56 cm (22½ inches) (> 97th percentile); weight, 4,423 gm (9 lb 12 ounces) (> 97th percentile); and head circumference, 40 cm (> 97th percentile).General development was within normal