RT Journal A1 TROSSMAN CM, ALZOFON FE T1 AN exchange transfusion formula JF A.M.A. Journal of Diseases of Children JO A.M.A. Journal of Diseases of Children YR 1959 FD December 1 VO 98 IS 6 SP 694 OP 698 DO 10.1001/archpedi.1959.02070020696004 UL http://dx.doi.org/10.1001/archpedi.1959.02070020696004 AB Introduction  The purpose of this paper is to present a simple formula permitting rapid calculation of the following data essential to the performance of an exchange transfusion for an infant, child, or adult: (a) the volume of donor blood needed; (b) the length of time required to perform the exchange transfusion; (c) the number of "unit exchanges" required; (d) the per cent exchange effected.The formula will be presented after a discussion of background material essential to its effective application. Four typical problems are then discussed, followed by a summary. Derivation of the formula and related subjects are given in an appendix.The Exchange Transfusion  Since 1946 the exchange transfusion has become the accepted method in treatment of erythroblastosis fetalis.1-3 Since 1950 exchange transfusions have been used to treat blood transfusion reactions4 and poisoning when conventional methods have failed. Poisoning by the following substances has been treated successfully