RT Journal A1 Touchette É, Petit D, Paquet J, Tremblay RE, Boivin M, Montplaisir JY T1 BEd-wetting and its association with developmental milestones in early childhood JF Archives of Pediatrics & Adolescent Medicine JO Archives of Pediatrics & Adolescent Medicine YR 2005 FD December 1 VO 159 IS 12 SP 1129 OP 1134 DO 10.1001/archpedi.159.12.1129 UL http://dx.doi.org/10.1001/archpedi.159.12.1129 AB Objective  To evaluate the relationship between bed-wetting and various developmental milestones in a large and representative sample of young children.Design  A randomized 3-level stratified survey design.Setting  Data were collected by questionnaires, and interviews were scheduled at home with the mother.Participants  A representative sample of children born from 1997 to 1998 in Quebec. A complete set of data on bed-wetting was obtained for 1666 children at the ages of 29, 41, and 53 months.Main Outcome Measures  Percentage of children who bed-wet and developmental factors associated with bed-wetting.Results  Approximately 10% of the children were bed-wetting at the age of 53 months. Bed-wetting cessation occurred for most children studied between the ages of 29 and 41 months. Motor skills were achieved by fewer boys who bed-wet compared with boys who did not (had sat up without support for 10 minutes at 5 months, P = .05; and had started crawling at 5 months, P<.01). More girls who bed-wet were prematurely born and had hyperactivity and inattention (P<.01 for all) compared with those who did not. Language milestones were achieved by fewer children who bed-wet compared with those who did not (boys: P = .04; girls: P = .02). No between-group difference was found for physical growth and sleep variables.Conclusions  These findings show an association between bed-wetting and developmental milestones in early childhood. This study supports that bed-wetting could be indicative of a possible delay in the development of the central nervous system and could act as a noticeable indicator for parents and pediatricians.