RT Journal
A1 Frush KS, Luo X, Hutchinson P, Higgins JN
T1 EValuation of a method to reduce over-the-counter medication dosing error
JF Archives of Pediatrics & Adolescent Medicine
JO Archives of Pediatrics & Adolescent Medicine
YR 2004
FD July 1
VO 158
IS 7
SP 620
OP 624
DO 10.1001/archpedi.158.7.620
UL http://dx.doi.org/10.1001/archpedi.158.7.620
AB Objectives 
    To introduce a simple method of dosing over-the-counter medication in a home setting using a color-coding concept and to compare dosing deviation from recommended dosage using the color-coded method with dosing deviation using conventional package labeling.Design 
    Randomized controlled clinical trial.Setting 
    Pediatric emergency center at a tertiary care medical center.Participants 
    A sample of 101 caregivers of children with nonemergent complaints separated into 2 groups. One group used a conventional dosing method and the other group used a color-coded method to determine and measure a dose of acetaminophen for their child.Main Outcome Measures 
    For both dose determination and dose measuring, percentage of deviation from recommended acetaminophen dosage was calculated and compared between the 2 groups.Results 
    There was no significant difference in sociodemographic characteristics between the 2 groups. How-ever, for dose determination, the average deviation (25.8% vs 1.7%) and median deviation (1% vs 0%) from recommended dosage were both higher for the group using conventional methods compared with the group using the color-coded method. The Wilcoxon rank sum test indicated that the median deviation was significantly different between the 2 groups (P<.001). Similar results were obtained for dose measuring. The average deviation (29% vs 0.5%) and the median deviation (17.2% vs 0%) from recommended dosage were higher for the group using conventional methods compared with the group using the color-coded method. The median deviation was also significantly different between the 2 groups (P<.001).Conclusion 
    This study suggests a marked improvement in caregivers' ability to correctly determine and measure an over-the-counter medication for their child using a color-coded method compared with conventional methods.